| Systemic disease | Estimated frequency of pericardial involvement (percent) | Type of pericardial involvement |
| Connective tissue diseases | ||
| Systemic lupus erythematosus | >50 | Pericardial effusion, pericarditis |
| Rheumatoid arthritis | 10-30 | Pericardial effusion (30 percent), pericarditis (10 percent) |
| Systemic sclerosis | Symptomatic (<20), overall (>60) | Pericardial effusion, pericarditis |
| Polymyositis and dermatomyositis | <10 | Pericarditis, pericardial effusion, cardiac tamponade (case reports) |
| Mixed connective tissue disease | 10-30 | Pericarditis, pericardial effusion |
| Sjogren syndrome | <30 | Pericarditis |
| Behcet disease | Rare | Pericarditis |
| Granulomatous diseases | ||
| Sarcoidosis | Rare | Pericardial effusion, pericarditis |
| Autoinflammatory diseases | ||
| Familial Mediterranean Fever (FMF) | 1 | Pericarditis |
| TNF receptor-1 associated periodic syndrome (TRAPS) | Rare | Pericarditis |
