Brain MRI and MR spectroscopy (MRS) of a 5-year-old with Sjogren-Larsson syndrome

(A) Image shows voxel locations in the occipital trigone (Box A) and in the central occipital gray matter (Box B).
(B) Proton MR spectra (TE = 20 msec) obtained from cerebral white matter (Spectrum C) and gray matter (Spectrum D). Note the presence of the high, sharp lipid peak at 1.3 ppm and a small peak at 0.8 to 0.9 ppm in the spectrum obtained from the white matter.