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Uptodate Reference Title
Increased risk of hypoglycemia with strict glycemic control
Increased risk of hypoglycemia with strict glycemic control
In the Diabetes Control and Complications Trial (DCCT), there was a progressive increase in the incidence of severe hypoglycemic episodes (per 100 patient-years) at lower attained A1C values during intensive insulin therapy in patients with type 1 diabetes.
A1C: glycated hemoglobin.
Data from: Diabetes Control and Complications Trial Research Group. The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. N Engl J Med 1993; 329:977.
