| Element | Value | Change from baseline |
| Uric acid | ≥476 micromol/L (8 mg/dL) | 25% increase |
| Potassium | ≥6.0 mmol/L (or 6 mEq/L) | 25% increase |
| Phosphorus | ≥2.1 mmol/L (6.5 mg/dL) for children or ≥1.45 mmol/L (4.5 mg/dL) for adults | 25% increase |
| Calcium | ≤1.75 mmol/L (7 mg/dL) | 25% decrease |
