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Histologic features of desquamative interstitial pneumonia

Histologic features of desquamative interstitial pneumonia
Key histologic features
Uniform involvement of lung parenchyma.
Prominent accumulation of alveolar macrophages (may show fine granular positivity with iron stains).
Mild to moderate fibrotic thickening of alveolar septa.
Mild interstitial chronic inflammation (lymphoid aggregates).
Pertinent negative findings
Dense and extensive fibrosis: inconspicuous or absent.
Smooth muscle proliferation: inconspicuous or absent.
Honeycomb fibrosis absent.
Fibroblastic foci and organizing pneumonia: inconspicuous or absent.
Eosinophils: inconspicuous, absent, or only focal.
Histologic_features_DIP.htm
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