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Major causes of mast cell-mediated angioedema

Major causes of mast cell-mediated angioedema
IgE-dependent allergic reactions
Foods
Drugs (antibiotics, local anesthetics, hormones)
Stinging insects
Latex
Contact (fresh fruits and vegetables, animal saliva)
Direct mast cell-mediator release
Opiates
Muscle relaxants (succinylcholine, curare)
Radiocontrast agents
Perturbations in arachidonic acid metabolism within mast cells
Aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs)
IgE: immunoglobulin E.
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