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Uptodate Reference Title
NCI CTCAE v5.0 pain
NCI CTCAE v5.0 pain
Adverse event
Grade 1
Grade 2
Grade 3
Grade 4
Grade 5
Pain
Mild pain
Moderate pain; limiting instrumental ADL*
Severe pain; limiting self-care ADL*
Pain is graded individually for many sites in the body and is characterized by the sensation of marked discomfort, distress, or agony.
NCI CTCAE: National Cancer Institute Common Terminology Criteria for Adverse Events; ADL: activities of daily living. * Instrumental ADLs include preparing meals, shopping, using the telephone, managing money. Self-care ADLs include bathing, dressing/undressing, using the toilet, taking medications, and not bedridden.