Lead author (publication date) | Gestational age, weeks | Previous uterine scar | Gravidity | Misoprostol dose (mcg) |
Ruptures of previously scarred uteri |
Jwarah (2007) | 8 | Yes | G3 | 800 miso PV |
Can (2020) | 11 | Yes | G3 | 400 miso PV |
Mazouni (2006) | 16 | Yes | ? | 600 mg mife followed 36 hours later by 200 miso PV every 3 hours up to 3 doses; miso doses repeated 24 hours later as needed |
Daskalaikis (2005) | 23 | Yes | G2 | 400 miso PO plus 400 PV given at first, then 400 PV dose 8 hours later |
Berghahn (2001) | 23 | Yes | G2(?) | 400 miso PV then 400 buccal 6 hours later |
Chen (1999) | 23 | Yes | G3 | 200 miso PV |
Mazouni (2006) | 24 | Yes | ? | 600 mg mife followed 36 hours later by 200 miso PV every 3 hours up to 3 doses; miso doses repeated 24 hours later as needed |
Nayki (2005) | 26 | Yes | G2(?) | 200 miso PV every 3 hours up to 4 doses |
Ruptures involving major malformation of uterus |
Samuels (2005) | 18 | No (pregnancy in noncommunicating rudimentary horn) | G1 | 200 miso PV |
Ruptures involving relatively high doses of misoprostol |
Phillips (1996) | 18 | No | G4 | 200 mg mife followed by 600 miso PV every 6 hours for 2 doses |
Ruptures involving high cumulative doses of misoprostol |
Bagga (2004) | 20 | No | G4 | 200 mg mife followed by 200 miso PV every 6 hours for 6 doses |
Letourneur (2002) | 25 | No | G1 | 600 mg mife followed by 200 miso PO for 7 doses |