| Serotonin syndrome (SS) | Neuroleptic malignant syndrome (NMS) | |
| Onset | Within 24 hours | Days to weeks |
| Neuromuscular findings | Hyperreactivity (tremor, clonus, reflexes) | Bradyreflexia, severe muscular rigidity |
| Causative agents | Serotonin agonist | Dopamine antagonist |
| Treatment agents | Benzodiazepine, cyproheptadine | Bromocriptine |
| Resolution | Within 24 hours | Days to weeks |
