Relationship of plasma antidiuretic hormone (ADH) concentrations to isosmotic changes in blood volume in the rat. Much higher ADH levels can occur with hypovolemia than with hyperosmolality, although a relatively large fall in blood volume is required before this response is initiated.
Data from Dunn FL, Brennan TJ, Nelson AE, et al. J Clin Invest 1973; 52:3212.
