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Prevalence of celiac disease in 17,201 Italian schoolchildren (age 6 to 15)

Prevalence of celiac disease in 17,201 Italian schoolchildren (age 6 to 15)
Test Percent positive
IgG and/or IgA antigliadin antibodies 7.50
IgA antigliadin and/or IgA endomysial antibodies 0.65
Intestinal biopsy performed 0.57
Villous atrophy seen on biopsy 0.44
Not biopsied but clinically celiac 0.04
Previously known celiac 0.06
TOTAL with diagnosis of celiac disease 0.54
IgG: immunoglobulin G; IgA: immunoglobulin A.
Adapted from: Catassi C, Fabiani E, Rätsch IM, et al. The coeliac iceberg in Italy: a multicentre antigliadin antibodies screening for coeliac disease in school-age subjects. Acta Paediatr Suppl 1996; 412:29.
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