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Laboratory findings during the evolution of iron deficiency anemia

Laboratory findings during the evolution of iron deficiency anemia
Test Storage iron deficiency Iron-limited erythropoiesis Iron-deficiency anemia
Hemoglobin Normal Normal Decreased
Transferrin saturation* Normal Decreased Decreased
Erythrocyte protoporphyrin Normal Increased Increased
Plasma ferritin Decreased Decreased Decreased
Reticulocyte hemoglobin content (CHr) or equivalent (Ret-He)  Normal  Decreased Decreased
* Transferrin saturation is calculated as the serum iron/total iron binding capacity (SI/TIBC).
¶ Ferritin is an acute phase reactant, and serum levels are increased by liver disease, inflammation, and malignancy. In these settings, it is not a good reflection of iron stores.
Graphic 57739 Version 5.0