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Historical clues to potential organic causes of poor weight gain in children

Historical clues to potential organic causes of poor weight gain in children
Historical clues Potential significance
Diarrhea Malabsorption (celiac disease, inflammatory bowel disease, cystic fibrosis, secondary lactase deficiency, food allergy, short bowel syndrome), excessive use of fructose-or sorbitol-based juices, diets high in sugar or other carbohydrates
Chronic constipation May cause decreased appetite
Abdominal pain Gastroesophageal reflux, esophagitis, chronic constipation
Vomiting or spitting up Gastroesophageal reflux, delayed gastric emptying, intestinal obstruction, food allergy/intolerance
Gagging, tactile hypersensitivity, prolonged feeding time Oral motor dysfunction
Decreased appetite Excessive juice (or other nonnutritious liquid) intake, chronic disease, medications, stressful psychosocial conditions
Recent travel to developing country, camping, housing in shelter, day care Infectious diarrhea (eg, giardiasis, nematodes, enteric pathogens)
Chronic otitis media Immune deficiency, structural abnormality that impairs intake
Snoring or mouth breathing Adenoidal hypertrophy
History of wheezing Mechanical obstruction (eg, vascular ring), chronic pulmonary disease
Polyuria, polydipsia, polyphagia Diabetes
Frequent infections Immune deficiency
Data from:
  1. Frank D, Silva M, Needlman R. Failure to thrive: Mystery, myth and method. Contemp Pediatr 1993; 10:114.
  2. American Academy of Pediatrics Committee on Nutrition. Failure to thrive. In: Pediatric Nutrition, 7th ed, Kleinman RE, Greer FR (Eds), American Academy of Pediatrics, Elk Grove Village, IL 2014. p.663.
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