Prostanoid synthesis and inhibition

Depiction of prostanoid synthesis and actions and potential levels of inhibition: 1. Aspirin and other nonsteroidal antiinflammatory drugs; 2. Alternative fatty acid substrates; 3. Glucocorticoids and selective PGHS-2 (COX-2) inhibitors; 4. Prostanoid receptor antagonists; 5. Nitric oxide synthase inhibitors, antihistamines; 6. Monoclonal antibodies to adhesion molecules.