Tests and evaluations | Donor | Candidate (allogeneic or autologous) |
History, review of systems, physical examination | + | + |
Dental evaluation | – | + |
Radiology | ||
Chest radiograph | – | + |
Pathogen-specific testing | ||
CMV IgG | + | + |
Hepatitis B (HBsAg, anti-HBsAg, anti-HBc) +/– viral load* | + | + |
Hepatitis C (IgM, IgG) | + | + |
Hepatitis C viral load¶ | + | – |
VZV IgG | + | + |
HSV IgG | – | + |
EBV (VCA IgG) | + | + (especially allogeneic and T cell-depleted) |
HIV-1, -2 antibodies | + | + |
HIV-1 viral load | + | – |
HTLV-1, -2 antibodies | + | + |
RPR or VDRL or a Treponema pallidum antibody test | + | + |
West Nile virus antibodiesΔ | +/– | – |
Serum Aspergillus galactomannan antigen◊ | – | +/– |
Toxoplasma gondii IgG | + | +/– (allogeneic only, particularly T cell-depleted) |
Screening for TB§ | – | + |
Staphylococcus aureus nasal culture | – | + |
Vancomycin-resistant Enterococcus rectal culture | – | + |
SARS-CoV-2 PCR on nasopharyngeal swab specimen | – | + |
Tests for individuals who have resided in or traveled to endemic areas | ||
Strongyloides stercoralis serology¥ | – | + |
Coccidioides spp serology‡ | – | +/– (especially allogeneic and T cell-depleted) |
Histoplasma capsulatum serology‡ | – | +/– (especially allogeneic and T cell-depleted) |
Trypanosoma cruzi serologyΔ† | + | +/– |
Malaria blood smears, rapid tests, and/or PCR** | + | + |
Zika virus exposure history¶¶ | + | – |