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Neurologic complications of chemotherapy, hormone therapy, and biological response modifiers

Neurologic complications of chemotherapy, hormone therapy, and biological response modifiers
Acute encephalopathy
Asparaginase
5-Azacytidine
BCNU (IA or HD)
Cisplatin
Corticosteroids
Cytarabine (HD)
Etoposide
Fludarabine
FU
Glucocorticoids
Hexamethylmelamine
Ifosfamide
Interferons
Interleukin-1 and -2
Methotrexate
Mitomycin C
Nelarabine
Nitrogen mustard
Pentostatin
Procarbazine
Sunitinib
Tamoxifen
Thiotepa (HD)
Tumor necrosis factor
Vinca alkaloids
Headaches
Asparaginase
Corticosteroids
Cytarabine (IT)
Etoposide
Fludarabine
Hexamethylmelamine
Interferons
Interleukins 1, 2, and 4
Mechlorethamine
Methotrexate (IT)
Nelarabine
Retinoic acid
Tamoxifen
Temozolomide
Thiotepa (IT)
Vasculopathies and "strokes"
Aflibercept
Antiangiogenic tyrosine kinase inhibitors (axitinib, cabozantinib, lenvatinib, pazopanib, ponatinib, regorafenib, sorafenib, sunitinib, vandetanib)
Asparaginase
BCNU (IA)
Bevacizumab
Cisplatin (IA)
Doxorubicin
Estramustine
Methotrexate
Ramucirumab 
Seizures
Asparaginase
BCNU
Busulfan (HD)
Cisplatin
Cytarabine (HD)
Dacarbazine
Enzalutamide
Etoposide
FU
Gemcitabine
Ifosfamide
Interferon
Interleukin-2
Methotrexate
Nelarabine
Nitrogen mustard
Pentostatin
Teniposide
Vinca alkaloids
Retinal toxicity
Alkylating agents (carboplatin, cisplatin, oxaliplatin, procarbazine)
Antimetabolites (capecitabine, cytarabine, fludarabine, methotrexate) 
BRAF inhibitors (dabrafenib, vemurafenib)
Docetaxel, paclitaxel 
Ipilimumab
MEK inhibitors (trametinib)
Tamoxifen, toremifene
Vincristine
Uveitis
Ipilimumab
Nivolumab
Rituximab
Vemurafenib
 Aseptic meningitis
Cytarabine (IT)
Methotrexate (IT)
Dementia
BCNU (IA and HD)
Cytarabine
Fludarabine
Interferon alfa
Methotrexate
Myelopathy
Cytarabine (IT)
Methotrexate (IT)
Thiotepa (IT)
Cranial neuropathy
BCNU (IA) (ototoxicity)
Cisplatin (ototoxicity, optic neuropathy)
Crizotinib (optic neuropathy)
Docetaxel, paclitaxel (optic neuropathy)
Imatinib (optic neuropathy)
Vincristine (extraocular palsies, optic neuropathy)
Neuropathy
5-Azacytidine
Bortezomib
Carboplatin
Cisplatin
Cytarabine (including Guillain-Barré syndrome)
Eribulin
Etoposide
FU
Gemcitabine
Hexamethylmelamine
Ifosfamide
Interferon alfa
Ipilimumab
Ivosidenib (Guillain-Barré syndrome)
Ixabepilone
Lenalidomide
Nelarabine (Guillain-Barré syndrome)
Paclitaxel
Procarbazine
Purine analogs (cladribine, fludarabine, nelarabine, pentostatin)
Suramin
Teniposide (VM-26)
Thalidomide
Tumor necrosis factor
Vinca alkaloids
Acute cerebellar syndrome
Capecitabine
Cytarabine (HD)
FU
Hexamethylmelamine
Procarbazine
Vinca alkaloids
BCNU: carmustine; IA: intraarterial; HD: high dose; FU: fluorouracil; IT: intrathecal.
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