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Agents responsible for reactive airways dysfunction syndrome

Agent	Type of investigation	Evidence	Reference
Acetic acid	Epidemiological	H, S, BHR	Am Rev Respir Dis 1991; 144:1058
Acetic acid	Case report	H, S, P	Br J Ind Med 1989; 46:67
Chloridic acid	Case report	H, S, BHR	Chest 1988; 94:476 Chest 1990; 98:928
Sulfuric acid	Case report	H, S, BHR	Chest 1988; 94:476
Various acids	Case report	H, S, BHR, P	Chest 1994; 105:1895
Various acids	Case report	H, S, BHR	Chest 1989; 96:297
Bleaching agent	Case report	H, S, BHR	Chest 1988; 94:476
Cleaning agents	Case report	H, S	Chest 1976; 69:372
Sealing agents	Case report	H, S, BHR	Chest 1985; 88:376
Ammonia	Case report	H, S	Mayo Clin Proc 1983; 58:389
Ammonia	Case report	H, S, P	Thorax 1992; 47:755
Phtalic anhydride	Case report	H, S, BHR	Rev Pneumol Clin 1993; 49:247
Bromochlorodifluoromethane (Halon 1211)	Case report	H, S, BHR	Occup Env Med 2004; 61:712
Bromotrifluoromethane (Halon 1301)	Case report	H, S	Eur Respir J 1999; 13:1192
Chlorine	Epidemiological	H, S, BHR	Occup Env Med 1994; 51:225
Chlorine	Clinical study	H, S, BHR, P	J Allergy Clin Immunol 1994; 93:12 Eur Respir J 1997; 10:241
Chlorofluorocarbons (CFC)	Clinical study	H, S, BHR, P	Scand J Work Environ Health 2003; 29:71
Chloropicrin	Experimental	P	Toxicol Appl Pharm 1984; 74:417
Metal coat remover	Case report	H, S, BHR	Chest 1985; 88:376
Diesel	Case report	H, S, BHR	J Occup Med 1993; 35:149
Diethylaminoethanol	Epidemiological	H, S	J Occup Med 1994; 36:623
Sulfur dioxide	Case report	H, S, BHR, P	Chest 1990; 98:928 Am Rev Respir Dis 1979; 119:555
Sulfur dioxide	Case report	H, S, BHR	Chest 1989; 96:297
Epichlorohydrin	Experimental	P	Toxicol Appl Pharm 1984; 74:417
Fire/smoke	Case report	H, S, BHR	Chest 1988; 94:476
Fire/smoke	Case report	H, S	J Occup Med 1991; 33:458
Formalin	Case report	H, S	Lancet 1975; 2:603
Formaldehyde	Case report	H, S, BHR	Allergy 2004; 59:115
Hydrazin	Case report	H, S, BHR	Chest 1985; 88:376
Iodine	Case report	H, S, BHR, P	Ind Health 2009; 47:681
Diisocyanates	Case report	H, S, BHR	Scand J Work Environ Health 1981; 7:310
	Case report	H, S, BHR, P	Allergy 1996; 51:262
	Experimental	S	Toxicol App Pharmacol 1987; 89:332
	Case report	H, S, BHR	Chest 1989; 96:297
Calcium oxide	Case report	H, S, BHR	Chest 1989; 96:297
Ethylene oxide	Case report	H, S, BHR, P	Br J Ind Med 1992; 49:523
Heated paints	Case report	H, S, BHR	Chest 1989; 96:297
Pulverized paints	Case report	H, S, BHR, P	Chest 1989; 96:297 Chest 1985; 88:376
Perchloroethylene	Case report	H, S, BHR	Chest 1988; 94:476
Vapors (chlorine, mustard, phosgene, etc)	Case report	H, P	Br Med J 1915; 165

H: history; S: spirometry; BHR: bronchial hyperresponsiveness; P: pathology.

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