Peripheral blood smear in a patient with chronic lymphocytic leukemia
Peripheral blood smear in a patient with chronic lymphocytic leukemia
Blood smear from a patient with B cell chronic lymphocytic leukemia. The predominant lymphocytes have a very sparse cytoplasm, round to slightly oval nuclei, and no evident nucleoli. Damaged lymphocytes ("smudge cells") are present (arrows).
From: Brunning RD, McKenna RW. Tumors of the bone marrow. Atlas of tumor pathology (electronic fascicle), Third series, fascicle 9, 1994, Washington, DC. Armed Forces Institute of Pathology.
