| May increase anti-clotting effect (and possibly increase risk of bleeding) | | Antibiotics | | Examples: Amoxicillin (brand name: Amoxil), amoxicillin-clavulanate (brand name: Augmentin), ciprofloxacin (brand name: Cipro), levofloxacin (brand name: Levaquin), metronidazole (brand name: Flagyl), trimethoprim-sulfamethoxazole (brand name: Bactrim); others | | Antifungals | | Example: Fluconazole (brand name: Diflucan); posaconazole (brand name: Noxafil), voriconazole (brand name: Vfend); others | | Hormones | | Examples: Methyltestosterone (brand name: Methitest), oxandrolone (brand name: Oxandrin), testosterone (brand names: Androderm, AndroGel, Axiron, Fortesta, Testim); others | | Antidepressants or nerve pain | | Examples: Amitriptyline (brand name: Elavil), duloxetine (brand name: Cymbalta), fluoxetine (brand names: Prozac, Sarafem), sertraline (brand name: Zoloft), venlafaxine (brand name: Effexor); others | | Cancer | | Examples: Capecitabine (brand name: Xeloda), fluorouracil, imatinib (brand name: Gleevec); tamoxifen (brand name: Nolvadex, Soltamox); others | | Cholesterol | | Examples: Fenofibrate (brand name: Lofibra, Tricor, Trilipix, others), gemfibrozil (brand name: Lopid), most statin drugs (brand names include: Crestor, Lescol, Mevacor, Zocor) | | Gout | | Allopurinol (brand names: Aloprim, Zyloprim) | | Heart | | Example: Amiodarone (brand names: Cordarone, Pacerone) | | Pain relievers and cough/cold medicines that contain aspirin or an NSAID | Examples: Aspirin, celecoxib (brand name: Celebrex), ibuprofen (brand names: Advil, Motrin), naproxen (brand names: Aleve, Naprosyn), tramadol (brand names: Ultram, Ultracet); others - Many over-the-counter pain relievers and cough/cold medicines contain an NSAID
- Always discuss all new medicines, including over-the-counter pain relievers and cough/cold medicines with your doctor
| | Stomach and heartburn relief | | Cimetidine (brand name: Tagamet), omeprazole (brand name: Prilosec) | | Steroids (glucocorticoids) | | Examples: Methylprednisolone (brand name: Medrol, Medrol Dose Pack), prednisone, prednisolone (brand name: Orapred); others | | | May decrease anti-clotting effect (and possibly increase risk of blood clots) | | Antibiotics and anti-tuberculosis medications | | Examples: Dicloxacillin, nafcillin, rifampin (brand names: Rifadin, Rifamate, Rifater), rifapentine | | Cancer | | Example: Enzalutamide (anti-androgen, brand name: Xtandi) | | Cholesterol | | Cholestyramine (brand names: Prevalite, Questran) | | Herbs | | Example: St. Johns wort | | Rheumatoid arthritis, transplant anti-rejection, control of immune system | | Azathioprine (brand name: Imuran) | | Seizures or nerve pain | | Examples: Carbamazepine (brand name: Tegretol), fosphenytoin (brand name: Cerebyx), phenobarbital (brand name: Luminal), phenytoin (brand name: Dilantin); others | | Stomach and nausea | | Aprepitant (brand name: Emend), fosaprepitant (brand name: Emend IV), sucralfate (brand name: Carafate) | | Vitamin K | | Avoid vitamin K supplements except the small amount in a daily multiple vitamin ("multivitamin") pill. If you take a multivitamin be sure to take it every day. If you stop taking a multivitamin, let your doctor know. | |
