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Rates of antibiotic nonsusceptible pneumococcal disease among children

Rates of antibiotic nonsusceptible pneumococcal disease among children
NS: nonsusceptible; MIC: minimum inhibitory concentration.
* The old/oral meningitis penicillin breakpoints classify isolates as penicillin nonsusceptible at a MIC ≥0.12 mcg/mL.
¶ Not susceptible to 3 or more of the antibiotic classes tested.
Δ The new parenteral penicillin breakpoints classify isolates as penicillin nonsusceptible at an MIC ≥4 mcg/mL for nonmeningitis disease and ≥0.12 mcg/mL for meningitis.
Data from: Hampton LM, Farley MM, Schaffner W, et al. Prevention of antibiotic-nonsusceptible Streptococcus pneumoniae with conjugate vaccines. J Infect Dis 2012; 205:401.
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