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Uptodate Reference Title
Red blood cell deformation in splenic cords
Red blood cell deformation in splenic cords
Scanning electron microphotograph of normal murine red blood cell passing from a splenic cord (below) through the sinusoidal barrier and into the splenic sinusoid (above). Note the deformation necessary to squeeze through the slit in the sinusoidal wall and how a surface area depleted spherocyte would be incapable of transversing the barrier.