| Increased destruction or consumption of platelets |
| Immune thrombocytopenia |
| Alloimmune thrombocytopenia |
| Autoimmune thrombocytopenia |
| Drug-induced immune thrombocytopenia |
| Sequestration and trapping |
| Hypersplenism |
| Kasabach-Merritt syndrome |
| Platelet activation and consumption |
| Disseminated intravascular coagulation |
| Thrombosis |
| Type 2B von Willebrand disease |
| Decreased production of platelets |
| Congenital thrombocytopenias |
| Drug-associated marrow suppression |
| Infiltrative bone marrow disorders |
| Preeclampsia |
| Miscellaneous causes |
| Infection: Both destructive and decreased production (ie, bone marrow suppression) can cause neonatal thrombocytopenia |
| Asphyxia: Mechanism uncertain |
| Dilution |
