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Role of oxidized LDL in atherosclerosis

Endothelial damage

Alteration in vascular tone

Monocyte/macrophage recruitment

Increased uptake of LDL by macrophages, with foam cell formation

Induction of growth factors

Increased platelet aggregation

Formation of autoantibodies to oxidized LDL

Oxidized_LDL_in_atheroscler.htm

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