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Uptodate Reference Title
Transdermal and oral estrogen prevent bone loss
Transdermal and oral estrogen prevent bone loss
Percent changes in lumbar spine bone density in postmenopausal women treated with transdermal or oral ERT or not treated. Each estrogen regimen led to an equivalent increase in bone density that was statistically different from the loss of bone in untreated women.
ERT: estrogen replacement therapy.
Data from: Stevenson JC, Cust MP, Gangar KF, et al. Effects of transdermal versus oral hormone replacement therapy on bone density in spine and proximal femur in postmenopausal women. Lancet 1990; 336:265.