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Uptodate Reference Title
Manometry of the stomach and small intestine differentiates neuropathic and myopathic disorders
Manometry of the stomach and small intestine differentiates neuropathic and myopathic disorders
Postprandial gastrointestinal motility in a patient with systemic sclerosis (myopathic disorder, left panel) is characterized by low amplitude contractions at all levels compared with controls. By comparison, a neuropathic disorder such as diabetes mellitus (right panel) is characterized by normal contraction amplitude, but abnormal organization of the contractile response. Specifically, there is a lack of distal antral contractions, pyloric tonic, and phasic pressure activity, and persistence of migrating motor complex-like activity postprandially (proximal jejunum rows 2 and 3) despite the ingestion of a solid-liquid meal.
Adapted from: Camilleri M. Medical treatment of chronic intestinal pseudo-obstruction. Pract Gastroenterol 1991; 15:10.