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Potential sources of growth hormone excess within the growth hormone axis

Potential sources of growth hormone excess within the growth hormone axis
(A) Normal axis
(B) Increased hypothalamic GHRH secretion
(C) Increased pituitary GH secretion
(D) Decreased SS tone
SS: somatostatin; GHRH: growth hormone-releasing hormone; GH: growth hormone; IGF-1: insulin-like growth factor-1.
Courtesy of Erica A Eugster, MD and Ora H Pescovitz, MD.
Graphic 51514 Version 3.0