| Osmoregulation | Volume regulation | |
| What is being sensed | Plasma osmolality | Effective circulating volume |
| Sensors | Hypothalamic osmoreceptors | Carotid sinus |
| Afferent glomerular arteriole | ||
| Atria | ||
| Effectors | ADH | Sympathetic nervous system |
| Renin-angiotensin-aldosterone | ||
| Natriuretic peptides | ||
| Pressure natriuresis | ||
| ADH | ||
| What is affected | Water excretion (via ADH) | Sodium excretion |
| Water intake (via thirst) |
