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Uptodate Reference Title
Typical conventional dosing schedule for venom immunotherapy: Schedule 1
Typical conventional dosing schedule for venom immunotherapy: Schedule 1
Week
Concentration, micrograms/mL
Volume, mL
1
1
0.05
2
1
0.1
3
1
0.2
4
1
0.4
5
10
0.05
6
10
0.1
7
10
0.2
8
10
0.4
9
100
0.05
10
100
0.1
11
100
0.2
12
100
0.4
13
100
0.6
14
100
0.8
15
100
1
16
100
1
18
100
1
21
100
1
Monthly
100
1
Injections are generally given weekly. The maintenance dose is achieved in most patients at week 15, after which the interval between injections is extended from weekly to every two weeks and then to monthly. This schedule is based upon the package insert for Hollister-Stier venom extracts.
Original figure modified for this publication. Reproduced with permission from: Golden DBK. Insect Allergy. In: Middleton's Allergy: Principles & Practice, 7th ed, Adkinson NF Jr, Bochner BS, Busse WW, et al (Eds), Mosby Elsevier, Philadelphia 2009. Illustrations used with the permission of Elsevier Inc. All rights reserved.
