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Hypothalamic-pituitary-testicular axis

Hypothalamic-pituitary-testicular axis
Schematic representation of the hypothalamic-pituitary-testicular axis shows the site of action of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) in the testes. Testosterone (T) and inhibin are produced by the testes. Testosterone has a negative feedback on hypothalamus and LH production, while inhibin has a negative feedback on FSH production.
GnRH: gonadotropin-releasing hormone; C: cholesterol.
Adapted from Griffin JE, Wilson JD. In: Metabolic Control and Disease, 8th ed, Bondy PK, Rosenberg LE (Eds), Saunders, Philadelphia 1980. p. 1535.
Graphic 50484 Version 4.0