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Plasma levels of endotoxins and outcomes in patients with sepsis

Plasma levels of endotoxins and outcomes in patients with sepsis
EA level
(EA units)		 SOFA score on admission
(mean ± SD)		 Shock
(percent)		 PaO2:FiO2 ratio
(mmHg; mean ± SD)		 Hospital mortality
(percent)
Low (<0.4) 4.3 ± 3.6 11.6 253 ± 111 16
Intermediate (0.4 to 0.59) 4.9 ± 3.9 20.5 215 ± 98 23
High (≥0.6) 5.7 ± 4.1 22.7 205 ± 102 23
EA: endotoxin activity; SOFA: sequential (or sepsis-related) organ dysfunction score; SD: standard deviation; PaO2: arterial pressure of oxygen; FiO2: fraction of inspired oxygen.
Adapted from: Marshall JC, Foster D, Vincent JL, et al. Diagnostic and prognostic implications of endotoxemia in critical illness: results of the MEDIC study. J Infect Dis 2004; 190:527.
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