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Uptodate Reference Title
Graph showing effect of dietary protein restriction on progression of diabetic nephropathy
Graph showing effect of dietary protein restriction on progression of diabetic nephropathy
Dietary protein restriction - to about 0.6 g/kg per day or 30 to 40 percent lower than the control group - in two trials (left and right panels) of patients with type 1 diabetes and diabetic nephropathy led to a 75 percent reduction in the rate of loss of glomerular filtration rate (GFR) at 18 to 36 months.
Data from: Walker JD, Bending JJ, Dodds RA, et al, Lancet 1989; 2:1411. Zeller K, Whittaker E, Sullivan L, et al. N Engl J Med 1991; 324:78.