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Calculator: Multinational Association for Supportive Care in Cancer (MASCC) risk index for patients with neutropenic fever (not appropriate for children <16 years of age)


Calculator: Multinational Association for Supportive Care in Cancer (MASCC) risk index for patients with neutropenic fever (not appropriate for children <16 years of age)

 
Burden of illness*

No or mild symptoms (5 points)

Moderate symptoms (3 points)

Severe symptoms (0 points)
Comorbidities

No hypotension (systolic blood pressure >90 mmHg) (5 points)

No chronic obstructive pulmonary disease (4 points)

Solid tumor or hematologic malignancy with no history of previous fungal infections** (4 points)

No dehydration requiring parenteral fluids (3 points)
Status

Outpatient status at the time of onset of the neutropenic fever syndrome (3 points)
Age

<60 years (2 points)

≥60 years (0 points)

 
Important: Inputs must be complete to perform calculation.

 
Total criteria point count:
 

 

MASCC risk index score interpretation

 
21 to 26 points: Patients at low risk for medical complications and those for whom outpatient management with an oral empiric antibacterial regimen may be safe and effective.
0 to 20 points: Patients at high risk for medical complications. High-risk patients require hospital admission for IV antibiotics and often require a prolonged hospitalization.

 
Notes
  • *Burden of illness refers to the general clinical status of the patient at the time of presentation with neutropenic fever. For additional guidance, please see appropriate UpToDate topic reviews that address risk assessment of patients with neutropenic fever.
  • ** Previous fungal infection refers to a demonstrated fungal infection or empirically treated fungal infection.

 
Only digits 0 to 9 and a single decimal point (".") are acceptable as numeric inputs. Attempted input of other characters into a numeric field may lead to an incorrect result.

Information on this page may not appear correctly if printed.

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