Your activity: 193 p.v.
your limit has been reached. plz Donate us to allow your ip full access, Email:

Calculator: Sokal score for chronic myeloid leukemia in adults

Calculator: Sokal score for chronic myeloid leukemia in adults

Age   years old
Spleen below costal margin  
Percent blasts   %

Important: Inputs must be complete to perform calculation.

Sokal score  



Sokal score interpretation

Sokal score <0.8: Low risk
Sokal score ≥0.8 and <1.2: Intermediate risk
Sokal score ≥1.2: High risk


  • The Sokal score is primarily used to stratify patients enrolled on clinical trials by disease aggressiveness.
  • In the original Sokal study of 813 patients with newly diagnosed chronic myeloid leukemia (CML) treated with chemotherapy (eg, busulfan), patients with low-risk disease had overall survival rates at 2 and 5 years of 90 and 81%, respectively.
  • By comparison, patients with high-risk disease had a 65% survival rate at 2 years. Survival rates have improved dramatically since the incorporation of tyrosine kinase inhibitors into the first-line treatment of patients with CML.

Equations used
Sokal_score = e(0.0116*(Age-43.4)+0.0345*(Spleen_below_costal_margin-7.51)+0.188*(sq(Platelets/700)-0.563)+0.0887*(Percent_blasts-2.1))


Only digits 0 to 9 and a single decimal point (".") are acceptable as numeric inputs. Attempted input of other characters into a numeric field may lead to an incorrect result.

Information on this page may not appear correctly if printed.

Legal Notices and Disclaimer

All information contained in and produced by the EBMcalc system is provided for educational purposes only. This information should not be used for the diagnosis or treatment of any health problem or disease. THIS INFORMATION IS NOT INTENDED TO REPLACE CLINICAL JUDGMENT OR GUIDE INDIVIDUAL PATIENT CARE IN ANY MANNER. Click here for full notice and disclaimer.

EBMcalc is Copyright © 1998-2023 Foundation Internet Services, LLC

Topic 16342 Version 7.0