Dermatologic infections: Infants, Children, and Adolescents: Topical: Cream, Ointment: Apply 3 to 4 times/day to affected area (Bradley 2017).
There are no dosage adjustments provided in the manufacturer's labeling. However, dosage adjustment unlikely due to low systemic absorption.
There are no dosage adjustments provided in the manufacturer's labeling. However, dosage adjustment unlikely due to low systemic absorption.
(For additional information see "Gentamicin (topical): Drug information")
Dermatologic infections: Topical: Apply 3 to 4 times daily to affected area.
There are no dosage adjustments provided in the manufacturer's labeling. However, dosage adjustment unlikely due to low systemic absorption.
There are no dosage adjustments provided in the manufacturer's labeling. However, dosage adjustment unlikely due to low systemic absorption.
Excipient information presented when available (limited, particularly for generics); consult specific product labeling.
Cream, External:
Generic: 0.1% (15 g, 30 g)
Ointment, External:
Generic: 0.1% (15 g, 30 g)
Yes
For external topical use only; not for ophthalmic use. Apply a small amount gently to the cleansed affected area; may cover with gauze dressing.
Topical: For external use only; not for ophthalmic use. Apply gently to affected area; may cover with gauze dressing. Remove crust of impetigo contagiosa prior to application.
Store at 15°C to 30°C (59°F to 86°F).
Topical treatment of superficial infections of the skin including folliculitis, impetigo contagiosa, furunculosis, sycosis barbae, ecthyma, pyoderma gangrenosum, infectious eczematoid dermatitis, pustular acne, pustular psoriasis, infected seborrheic dermatitis or contact dermatitis, infected excoriations and bacterial super-infections of fungal or viral infections (FDA approved for ages >1 year and adults)
Gentamicin may be confused with gentian violet, kanamycin, vancomycin
The following adverse drug reactions and incidences are derived from product labeling unless otherwise specified.
Frequency not defined.
Dermatologic: Erythema, pruritus
Hypersensitivity to gentamicin or any component of the formulation
Concerns related to adverse effects:
• Superinfection: Prolonged use may result in fungal or bacterial superinfection; discontinue if superinfection is noted.
• Sensitization: Topical use has been associated with local sensitization (redness, irritation); discontinue if sensitization is noted.
Other warnings/precautions:
• Long-term use: Not intended for long-term therapy.
None known.
Note: Interacting drugs may not be individually listed below if they are part of a group interaction (eg, individual drugs within “CYP3A4 Inducers [Strong]” are NOT listed). For a complete list of drug interactions by individual drug name and detailed management recommendations, use the Lexicomp drug interactions program
There are no known significant interactions.
Interferes with bacterial protein synthesis by binding to 30S ribosomal subunit resulting in a defective bacterial cell membrane
Absorption: Systemic absorption is reported following topical application to burn patients (Sawchuk 1980).
Cream (Gentamicin Sulfate External)
0.1% (per gram): $3.29
Ointment (Gentamicin Sulfate External)
0.1% (per gram): $3.29
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