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Calculator: Crohn's Disease Activity Index (CDAI) in adults


Calculator: Crohn's Disease Activity Index (CDAI) in adults

 
Input
 
Sex Female (0)

Male (1)
Weight  
Height  
Hematocrit  
Average number of liquid or soft stools per day over 7 days (14 points per stool)  
Using diphenoxylate or loperamide for diarrhea
 No (0)
 Yes (30)
Average abdominal pain rating over 7 days
 None (0)
 Mild pain (35)
 Moderate pain (70)
 Severe pain (105)
General wellbeing each day over 7 days
 Well (0)
 Slightly below average (49)
 Poor (98)
 Very poor (147)
 Terrible (196)
Arthritis or arthralgia
 No (0)
 Yes (20)
Iritis or uveitis
 No (0)
 Yes (20)
Erythema nodosum, pyoderma gangrenosum, or aphthous stomatitis
 No (0)
 Yes (20)
Anal fissure, fistula, or abscess
 No (0)
 Yes (20)
Other fistula
 No (0)
 Yes (20)
Temperature over 100°F (37.8°C) in the last week
 No (0)
 Yes (20)
Finding of an abdominal mass
 No mass (0)
 Possible mass (20)
 Definite mass (50)

 
Results
 
Important: Inputs must be complete to perform calculation.

 
 
Standard weight  
Weight deviation points  
Absolute hematocrit deviation  
CDAI  
 

 

 

CDAI interpretation

 
0 to 149 points: Asymptomatic remission
150 to 220 points: Mildly to moderately active Crohn disease
221 to 450 points: Moderately to severely active Crohn disease
451 to 1100 points: Severely active to fulminant disease

 
 

 
Notes
  • Patients requiring glucocorticoids to remain asymptomatic are not considered to be in remission but are referred to as being "glucocorticoid dependent."
  • Absolute deviation of hematocrit is simply the difference in hematocrit from standard. As an example, a male patient with a hematocrit of 40% has an absolute deviation of 7.
  • Percent deviation from standard weight is (1 - weight/standard weight) * 100, thus positive percent deviation represents weight loss, adding points to the CDAI.
  • Please refer to appropriate UpToDate topic reviews for further information.
  • Standard weight is calculated as follows:
     
    Standard weight for males (kg) = (height in m)2 x 22.1 (kg/m2)
    Standard weight for females (kg) = (height in m)2 x 20.8 (kg/m2)

 
Equations used
 
Standard weight = (1 if the following expression is true, 0 if false)(Sex == 0) * ((Height/100)2 * 20.8) + (1 if the following expression is true, 0 if false)(Sex == 1) * ((Height/100)2 * 22.1)
Weight deviation points = 100 * (1 - (Weight / Standard weight))
Absolute hematocrit deviation = (1 if the following expression is true, 0 if false)(Sex == 0) * (42 - Hematocrit) + (1 if the following expression is true, 0 if false)(Sex == 1) * (47 - Hematocrit)
Stool count factor = Average number of liquid or soft stools per day over 7 days (14 points per stool) * 14
CDAI = Stool count factor + Using diphenoxylate or loperamide for diarrhea + Average abdominal pain rating over 7 days + General wellbeing each day over 7 days + Arthritis or arthralgia + Iritis or uveitis + Erythema nodosum, pyoderma gangrenosum, or aphthous stomatitis + Anal fissure, fistula, or abscess + Other fistula + Temperature over 100°F (37.8°C) in the last week + Finding of an abdominal mass + Weight deviation points + (6 * Absolute hematocrit deviation)

 

 
Equation parameters, such as Sex, have two or more discrete values that may be used in the calculation. The numbers in the parentheses, eg, (0), represent the values that will be used.
 

 
Only digits 0 to 9 and a single decimal point (".") are acceptable as numeric inputs. Attempted input of other characters into a numeric field may lead to an incorrect result.

Information on this page may not appear correctly if printed.

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Topic 15646 Version 15.0