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Calculator: Hepatitis discriminant function for estimating disease severity in adults with alcoholic hepatitis


Calculator: Hepatitis discriminant function for estimating disease severity in adults with alcoholic hepatitis

 
Input
 
Prothrombin time  
Control prothrombin time  
Bilirubin  

 
Result
 
Important: Inputs must be complete to perform calculation.

 
 
Index  
 

 
 

 
Notes
  • Patients with an index ≥32 may benefit from treatment with glucocorticoids.
  • Please refer to appropriate UpToDate topic reviews for further information.

 
Equations used
 
Index = 4.6 * (Prothrombin_time - Control_prothrombin_time) + Bilirubin

 

 
References
  1. Ramond MJ, Poynard T, Rueff B, et al. A randomized trial of prednisolone in patients with severe alcoholic hepatitis. N Engl J Med 1992; 326:507.
  2. Friedman SL, McQuaid KR, Grendell JH, et al. Current Diagnosis & Treatment in Gastroenterology, 2nd ed, McGraw-Hill Medical 2002.
Only digits 0 to 9 and a single decimal point (".") are acceptable as numeric inputs. Attempted input of other characters into a numeric field may lead to an incorrect result.

Information on this page may not appear correctly if printed.

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Topic 15641 Version 11.0