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Calculator: Serum anion gap (conventional and SI units)

Calculator: Serum anion gap (conventional and SI units)

Na   mEq/L [mmol/L]
Cl   mEq/L [mmol/L]
HCO3   mEq/L [mmol/L]

Important: Inputs must be complete to perform calculation.

Serum anion gap   mEq/L
Decimal precision  


  • The serum anion gap is calculated from the difference between the major measured serum cation (Na) and measured anions (Cl + HCO3).
  • The normal value varies among laboratories and must be known for proper assessment.
  • Clinical use of the anion gap calculation is discussed in appropriate UpToDate topics.

Equations used
Serum anion gap = Na - (Cl + HCO3)

Only digits 0 to 9 and a single decimal point (".") are acceptable as numeric inputs. Attempted input of other characters into a numeric field may lead to an incorrect result.

Information on this page may not appear correctly if printed.

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