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Calculator: Clinical criteria for exudative pleural effusion in adults (pleural fluid only-3 criteria)


Calculator: Clinical criteria for exudative pleural effusion in adults (pleural fluid only-3 criteria)

 
Input
 
Pleural fluid protein  
Pleural fluid cholesterol  
Pleural fluid LDH  
Upper limit of normal serum LDH  

 
Results
 
Important: Inputs must be complete to perform calculation.

 
 
Pleural fluid LDH to upper limit of normal serum LDH ratio  
 
Decimal precision  

 

 

Pleural fluid interpretation

 
Criteria for an exudative effusion (criteria met are  highlighted )
Pleural fluid protein >3.0 g/dL [30 g/L]
Pleural fluid cholesterol >55 mg/dL [1.42 mmol/L]
Pleural fluid LDH to upper limit of normal ratio serum LDH >0.66666
Classification
Transudative effusion is likely
Exudative effusion is likely

 
 

 
Notes
  • If the Pleural fluid protein is >3.0 g/dL [>30 g/L], then an exudate is likely.
  • If the Pleural fluid cholesterol is >55 mg/dL [>1.42 mmol/L], then an exudate is likely.
  • If the Pleural fluid LDH is greater than two-thirds the upper limit of the laboratory’s normal serum LDH, then an exudate is likely.
  • Please refer to UpToDate topic review on evaluation of pleural effusions for more information.
  • LDH: lactate dehydrogenase enzyme activity; PFP: pleural fluid protein; PFL: pleural fluid LDH; SL: serum LDH; ULN: upper limit normal.

 
Equations used
 
PFL_to_ULN_SL_ratio = PFL / ULN_SL

 

 
Only digits 0 to 9 and a single decimal point (".") are acceptable as numeric inputs. Attempted input of other characters into a numeric field may lead to an incorrect result.

Information on this page may not appear correctly if printed.

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Topic 139616 Version 1.0