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Uptodate Reference Title
Comparison of antibiotics versus appendectomy for nonperforated appendicitis
Comparison of antibiotics versus appendectomy for nonperforated appendicitis
Antibiotics
Appendectomy
Advantages
Avoid surgery and anesthesia
Shorter duration of disability compared with surgery
Not associated with an increased risk of appendix rupturing compared with surgery
Appendicitis almost never recurs after appendectomy
Lower incidence of subsequent hospitalization than nonoperative management
Disadvantages
10 to 20% failure rate at 30 days*
30 to 40% recurrence rate at 1 year*
40 to 50% recurrence rate at 5 years*
Small risk of missed neoplasm (mostly in older patients)
Requires surgery and anesthesia
Longer duration of disability required to recover from surgery
* The lower percentage has been reported by trials excluding patients with appendicolith; the higher percentage has been reported by trials including patients with appendicolith.
Reference:
Talan DA, Di Saverio S. Treatment of acute uncomplicated appendicitis. N Engl J Med 2021; 385:1116.