Histologic features of esophageal mucosal epithelium in pill-induced esophagitis (A-E) and reflux esophagitis (F).
(A) Intraepithelial eosinophil
infiltration with microabscess.
(B) Mixed infiltration of eosinophils and
neutrophils.
(C) Intraepithelial pustules.
(D) Dilated intercellular spaces (upper), and extensive vacuolization of epithelial cells (lower).
(E) Subepithelial papillae extending three-fourths of the epithelial thickness.
(F) Reactive atypia with vesicular nucleus and prominent nucleolus (H&E stain).