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Initial laboratory and imaging evaluation for poor weight gain in children younger than 2 years in resource-abundant countries

Initial laboratory and imaging evaluation for poor weight gain in children younger than 2 years in resource-abundant countries
Test(s) Rationale
Basic tests (performed in most children)
CBC, CRP, ESR
  • Screen for anemia, chronic infection, inflammation, malignancy
Urinalysis, urine culture
  • Screen for protein or carbohydrate loss (eg, glucosuria) and indolent kidney disease (eg, renal tubular acidosis, UTI)
Additional tests for initial evaluation if clinically indicated by the history or examination
  • Electrolytes, BUN, creatinine, glucose
  • Calcium, phosphorus, magnesium
  • Albumin, total protein, liver enzymes
  • Amylase, lipase
  • Prealbumin
  • Evaluation of kidney, liver, and pancreatic disease
  • Assessment of nutritional status
Stool studies:
  • Guaiac, leukocytes
  • Routine culture, ova and parasite smears
  • Giardia antigen
  • Evaluate gastrointestinal infection
Chest radiograph
  • Evaluate cardiopulmonary disease
CBC: complete blood count; CRP: C-reactive protein; ESR: erythrocyte sedimentation rate; UTI: urinary tract infection; BUN: blood urea nitrogen.
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