hCG: human chorionic gonadotropin; TSH: thyroid-stimulating hormone; PRL: prolactin; FSH: follicle-stimulating hormone.
* The diagnosis of perimenopause/menopause in females over age 45 years is clinical and based upon the presence of irregular menses and/or menopausal symptoms. Laboratory evaluation is not necessary or suggested.
¶ In females ages 40 to 45, the presence of irregular menses and hot flashes strongly suggests menopause. However, laboratory evaluation should be performed first to rule out other endocrine disorders.
Δ Diagnostic criteria for early menopause: irregular menses, hot flashes, without another endocrine disorder (thyroid disease, hyperprolactinemia).