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Types of HCT and risk of AKI

Types of HCT and risk of AKI
Donor relationship Type of conditioning Exposure to CNI Risk for AKI Development of SOS Risk for cGVHD
Allogeneic Myeloablative High 19 to 66% High High
Allogeneic Nonmyeloablative High 29 to 54% Low High
Autologous Myeloablative None 12 to 50% Moderate None
HCT: hematopoietic cell transplantation; AKI: acute kidney injury; CNI: calcineurin inhibitor; SOS: sinusoidal obstruction syndrome; cGVHD: chronic graft-versus-host disease.
Reproduced with permission from: Hingorani S. Chronic kidney disease in long-term survivors of hematopoietic cell transplantation: epidemiology, pathogenesis, and treatment. J Am Soc Nephrol 2006; 17:1995. Copyright © 2006 American Society of Nephrology. All rights reserved.
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