Persistent symptom¶ | Proportion of patients affected by symptom | Approximate time to symptom resolutionΔ |
Common physical symptoms | ||
Fatigue | 15 to 87%[1,2,6,9,14,16] | 3 months or longer |
Dyspnea | 10 to 71%[1,2,6-9,14] | 2 to 3 months or longer |
Chest discomfort | 12 to 44%[1,2] | 2 to 3 months |
Cough | 17 to 34%[1,2,9,12] | 2 to 3 months or longer |
Anosmia | 10 to 13%[1,3-5,9,11] | 1 month, rarely longer |
Less common physical symptoms | ||
Joint pain, headache, sicca syndrome, rhinitis, dysgeusia, poor appetite, dizziness, vertigo, myalgias, insomnia, alopecia, sweating, and diarrhea | <10%[1,2,8,9,11] | Unknown (likely weeks to months) |
Psychologic and neurocognitive | ||
Post-traumatic stress disorder | 7 to 24%[6,10,14] | 6 weeks to 3 months or longer |
Impaired memory | 18 to 21%[6,15] | Weeks to months |
Poor concentration | 16%[6] | Weeks to months |
Anxiety/depression | 22 to 23%[2,7,8,10,12-14] | Weeks to months |
Reduction in quality of life | >50%[8] | Unknown (likely weeks to months) |
COVID-19: coronavirus disease 2019.
* These data are derived from an earlier period in the pandemic; information on patient recovery and persistent symptoms is evolving, and these figures may change as longer-term data emerge.
¶ More than a third of patients with COVID-19 experience more than one persistent symptom.
Δ Time course for recovery varies depending on premorbid risk factors and illness severity and may be shorter or longer than that listed. Hospitalized patients, and in particular critically ill patients, are more likely to have a more protracted course than those with mild disease.