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Histopathologic features of granulomatous-lymphocytic interstitial lung disease

Histologic features of granulomatous-lymphocytic interstitial lung disease (GLILD).
(A) Lymphocytic interstitial pneumonitis. Diffuse, lymphocytic interstitial infiltrates obliterating the alveolar spaces in some areas (100×).
(B) Follicular bronchiolitis. Nodular, lymphoid peribronchiolar aggregates (100×).
(C) Non-necrotizing granuloma with multinucleated giant cells (arrow; 200×). Hematoxylin and eosin staining.

Reproduced from: Baumann U, Routes JM, Soler-Palacin P, et al. The lung in primary immunodeficiencies: New concepts in infection and inflammation. Front Immunol 2018; 9:1837. Available at: https://www.frontiersin.org/articles/10.3389/fimmu.2018.01837/full. Copyright © 2018 The Authors. Reproduced under the terms of the Creative Commons Attribution License 4.0.

Graphic 130044 Version 1.0