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Uptodate Reference Title
International Pediatric Liver Tumors Consensus Classification of Hepatoblastoma
International Pediatric Liver Tumors Consensus Classification of Hepatoblastoma
Epithelial
Fetal
Fetal with low mitotic activity (well differentiated)
Fetal, mitotically active (crowded fetal)
Pleomorphic
Embryonal
Small cell undifferentiated
SMARCB1 (INI1)-negative
SMARCB1 (INI1)-positive
Cholangioblastic
Macrotrabecular
Mixed epithelial (any/all above)
Mixed epithelial and mesenchymal
Without teratoid features
With teratoid features
SMARCB1: SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin, subfamily B, member 1; INI1: integrase interactor-1.
Adapted by permission from Macmillan Publishers Ltd: Modern Pathology. López-Terrada D, Alaggio R, de Dávila MT, et al. Towards an international pediatric liver tumor consensus classification: proceedings of the Los Angeles COG liver tumors symposium. Mod Pathol 2014; 27:472. https://www.nature.com/modpathol/.
