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Uptodate Reference Title
Evaluation of primary amenorrhea: Uterus present
Evaluation of primary amenorrhea: Uterus present
hCG: human chorionic gonadotropin; FSH: follicle-stimulating hormone; TSH: thyroid-stimulating hormone; PRL: prolactin; T: testosterone; POI: primary ovarian insufficiency; PCOS: polycystic ovary syndrome; GnRH: gonadotropin-releasing hormone; MRI: magnetic resonance imaging. * Primary amenorrhea is defined as lack of menses by age 13 and no breast development, or lack of menses by age 15 and breast development is present. ¶ Refer to UpToDate topics on the evaluation of secondary amenorrhea for discussion of hyperprolactinemia, thyroid disease, and PCOS. These patients usually present with secondary rather than primary amenorrhea. Δ Pituitary MRI not required in those with clear explanation for their hypogonadotropic amenorrhea, eg, celiac disease or type 1 diabetes mellitus.