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Worksheet for calculation of the melanoma-specific GPA

Worksheet for calculation of the melanoma-specific GPA
Prognostic factor GPA Patient score
0 0.5 1.0 1.5 2.0
KPS ≤70 80 90-100      
Age, years ≥70 <70        
Number of BM ≥5 2-4 1      
ECM Present   Absent      
BRAF Negative or unknown Positive        
  Sum = median survival by GPA:
0-1 = 5 months; 1.5-2.0 = 8 months;
2.5-3.0 = 16 months; 3.5-4.0 = 34 months
GPA: graded prognostic assessment; KPS: Karnofsky Performance Status; BM: brain metastases; ECM: extracranial metastases.
From: Sperduto PW, Mesko S, Li J, et al. Survival in patients with brain metastases: Summary report on the updated diagnosis-specific graded prognostic assessment and definition of the eligibility quotient. J Clin Oncol 2020; 38:3773. DOI: 10.1200/JCO.20.01255. Copyright © 2020 American Society of Clinical Oncology. Reproduced with permission from Wolters Kluwer Health. Unauthorized reproduction of this material is prohibited.
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