Clinical parameters | Score | Comments |
–1 | 0 | 1 |
Fever ≥101.3°F (38.5°C) | No/unknown | Yes | | |
Lymphadenopathy | | No/unknown | Yes | >1 cm, at least 2 sites |
Eosinophilia ≥0.7 × 109 or ≥10% if leucopenia | | No/unknown | Yes | Score 2 points of ≥1.5 × 109 |
Atypical lymphocytes | | No/unknown | Yes | |
Skin rash |
| No | Unknown | Yes | Suggestive features: ≥2 facial edemas, purpura, infiltration, desquamation |
| | No/unknown | Yes |
Skin biopsy suggestive of DRESS | No | Yes/unknown | | |
Organ involvement | | No | Yes | 1 point for each organ involvement, maximum score: 2 |
Disease duration ≥15 days | No/unknown | Yes | | |
Exclusion of other causes | | No/unknown | Yes | 1 point if 3 of the following tests are performed and are negative: HAV, HBV, HCV, mycoplasma, chlamydia, ANA, blood culture |