Gastric biopsy sampling protocol

(Panel A) Sydney protocol biopsy sites in the anatomic view.
(Panel B) Sydney protocol biopsy sites in the opened stomach along the greater curvature.
Gastric biopsies should be obtained from the following sites:
1. Distal antrum, lesser curvature, within 3 to 5 cm of pylorus
2. Distal antrum, greater curvature, within 3 to 5 cm of pylorus
3. Lesser curvature of the incisura angularis
4. Proximal corpus, lesser curvature
5. Proximal corpus, greater curvature

Adapted from: Nieuwenburg SA, Waddingham WW, Graham D. Accuracy of endoscopic staging and targeted biopsies for routine gastric intestinal metaplasia and gastric atrophy evaluation study protocol of a prospective, cohort study: the estimate study. BMJ Open 2019; 9:e032013. Copyright © 2019 The Authors. Available at: https://bmjopen.bmj.com/content/9/9/e032013 (Accessed on February 18, 2020). Reproduced under the terms of the Creative Commons Attribution License.

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